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Clinical evidence for Alma platforms

Alma platforms are supported by peer-reviewed clinical studies. This page lists the published evidence by platform, with a link to each paper. It is written for clinic owners and practitioners who want to check the science before they buy, and for anyone comparing devices. Every study below is also in our Clinical Resources library, where you can filter by platform and indication.

How to read it. Journal, year and first author are shown for each study. Where a study was performed on an earlier Alma platform that shares the same technology, the section note says so. Treatment outcomes in these papers were obtained under study conditions; results in practice vary with patient selection, settings and operator skill, which is why Alma Lasers Australia trains every clinic on protocol.

Jump to: Alma Soprano (Titanium SE, ICE Platinum, ICE) · Harmony XL Pro and Alma Harmony · Alma Hybrid · Alma Pixel CO2 · Alma PrimeX · Accent Prime · Fractional microplasma (Alma Opus) · Alma Q · Alma Duo

Alma Soprano (Titanium SE, ICE Platinum, ICE): laser hair removal

Seven peer-reviewed studies on the triple-wavelength and 810 nm diode platforms, including efficacy and safety in skin types IV to V. Product page.

Harmony XL Pro and Alma Harmony: skin platform

Vascular lesions, photodamage, texture, acne scars and tattoo removal across the Harmony applicators, including Dye-VL narrowband light, ClearLift Q-switched Nd:YAG and the 1540 nm fractional erbium:glass. Product page.

Alma Hybrid: CO2 and 1570 nm resurfacing

Studies on the dual CO2 and 1570 nm approach, including periorbital rejuvenation and the histological basis for sequential application. Alma Hybrid supplied by Alma Lasers Australia is included in the ARTG (321320). Product page.

Alma Pixel CO2: fractional CO2 resurfacing

Fractional CO2 resurfacing, acne scarring, keloid management and laser-assisted drug delivery. Alma Pixel CO2 is included in the ARTG (323941). Product page.

Alma PrimeX: body contouring

Pulsed ultrasound with unipolar radiofrequency for circumference reduction and contouring. Product page.

Accent Prime: radiofrequency and ultrasound

Radiofrequency and ultrasound for lipolysis, skin tightening, cellulite, pore size and non-surgical periorbital tightening. Product page.

Fractional microplasma (Alma Opus)

Microplasma radiofrequency studies on scars, striae and post-burn pigmentation. Several were conducted on Alma's earlier microplasma platform; the technology carries through to Alma Opus. Product page.

Alma Q: Q-switched Nd:YAG

Q-switched 1064 nm studies on post-surgical scars, hyperpigmentation in skin types IV to V, active acne and non-ablative rejuvenation. Product page.

Alma Duo: low-intensity shockwave for erectile dysfunction

Three systematic reviews and meta-analyses of low-intensity extracorporeal shockwave therapy, the technology class Alma Duo belongs to. Product page.

Evidence in Australian practice

Alma Lasers Australia is building a library of Australian case series with clinics that agree to share anonymised before-and-after results for local skin types and sun exposure. If your clinic would like to contribute, or you want the full text of any study above, contact your Alma representative or get in touch.

Questions clinics ask about the evidence

Are these studies on the exact devices sold in Australia?

Most are on the current platforms. Where a paper used an earlier Alma platform sharing the same technology, such as the microplasma studies, the section note says so. Devices supplied by Alma Lasers Australia are the current models, included in the ARTG.

Why are some studies small?

Aesthetic device research often starts with pilot and split-face studies, then builds to larger series and systematic reviews. The list mixes both so you can see the progression. Ask your representative for the papers most relevant to your indication.

Does Alma publish Australian data?

Australian case series are being collected now with participating clinics; see the section above. Alma Academy sessions also present Australian practitioner experience with local skin types.

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